Job Description

Biotechnology company is hiring a Research Associate II to join the Peptide Therapeutics department to support discovery efforts. The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.

This is a 3-year contract onsite in South San Francisco, California.

Responsibilities:

• Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins.
• Handle phage libraries, including amplification, titration, panning, and rescue procedures.
• Design and execute ELISA-based binding assays for hit validation and screening.
• Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
• Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
• Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion.
• Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
• Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.

Qualifications

• B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
• Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
• Proficiency in ELISA, western blot, and high-throughput screening methods.
• Familiarity with Next Generation Sequencing data analysis and experience with laboratory automation platforms.
• Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.

Salary

• $84,052-$92,456

Why Choose R&D Partners?

As an employee, you have access to a comprehensive benefits package including:

• Medical insurance – PPO, HMO & HSA
• Dental & Vision insurance
• 401k plan
• Employee Assistance Program
• Long-term disability
• Weekly payroll
• Expense reimbursement
• Online timecard approval

R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.

R&D Partners is an equal-opportunity employer.

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